石家庄市格林─巴利综合征流行病学特征兼与欧美特征的比较

Epidemiologic features of Guillain-Barre syndrome in Shijiazhuang city and comparison with those in Europe and America

我们对１９７５～１９９３年石家庄市格林─巴利综合征（ＧＢＳ）的流行病学特征进行了研究，这一地区的年均发病率为０．５８／１０万，１９年间的长期发病率有显著的波动，出现了两个流行高峰和一个流行周期，发病有明显的夏秋季的季节性和周期性的地区丛集现象，具有青少年高发的特点，这些不同于欧美ＧＢＳ的流行病学特征，提示石家庄市的ＧＢＳ可能主要是由一种传染性致病因子所致。

We studied the epidemiologic features of Guillain-Barre syndrome(GBS)in Shijiazhuang city during the preiod from 1975 to 1993. The mean annual incidence rate was 0.58 per 100,000 population. Incidence significantly fluctuated With time.There were two epidemic peaks and one epidemic cycle. The clear seasonal clusteringsoccurred in summer and autumn. There were periodic geographic clusterings. The higher incidence was in children and young adults. These epidemiologic features differing from those in Europe and America suggested that GBS in Shijiazhuang city may be mainly caused by one infectious agent.