胰腺局部组织肾素-血管紧张素-醛固酮系统与胰腺炎
被引量：1
摘要
组织局部肾素-血管紧张素-醛固酮系统(RAAS)与组织循环、纤维化等关系密切,胰腺存在局部RAAS,并可能在胰腺循环调控、外分泌调节中起重要作用。胰腺炎时胰腺局部RAS异常激活,可能主要通过对局部组织循环的影响参与AP的发病和重症化,并且通过其致纤维化作用参与CP的发病。ACEI和ARB对大鼠胰腺炎具有良好防治效果,已在胰腺炎治疗中显示出一定前景。
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