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硫代硫酸钠缓解色素内镜所致食管粘膜刺激症状的研究 被引量:4

The clinical trial for relief of irritation on esophageal mucosa caused by chromoendoscopy with sodium thiosulate solution
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摘要 目的:探索Lugol’s液色素内镜检查后缓解食管粘膜刺激症状的方法。方法:患者经色素内镜检查后随机分为3组:A组喷洒30ml的5%硫代硫酸钠溶液(STS);B组口服30ml硫糖铝混悬液;C组喷洒STS后口服硫糖铝混悬液。完成上述治疗后30min,采用问卷形式调查患者急性食管粘膜刺激症状以及症状缓解情况。结果:107例患者中,60例出现不同程度的食管粘膜刺激症状,经各组相应处理后,A组18例,B组7例,C组18例的食管粘膜刺激症状在30min内缓解,A、C组与B组比较食管粘膜刺激症状可显著减轻。结论:喷洒STS可有效缓解或减轻Lugol’s液染色后所致的食管粘膜刺激症状。 Objective, To investigate the method of easing esophageal mucosal irritation symptoms induced by Lugol's staining in chromoendoscopy. Methods: Patients were randomized into 3 groups after Lugol's chromoendoscopy, group A was sprayed 30ml of 5 % sodium thiosulate solution (STS) ,group B took 30 ml sucralfate suspension and group C was sprayed 30 ml of 5% STS and took 30 ml sucralfate suspension sequentially. The patients were asked to complete a questionnaire on acute and late adverse symptoms 30 minutes later. Results: 60 patients reported some acute adverse symptoms after examination. After corresponding treatment, there were 18 patients in group A, 7 patients in group B and 18 patients in group C whose irritation symptoms had alleviated in 30 minutes, Group A and group C could significantly reduce adverse symptoms compared with group B. Conclusion:Spraying STS can effectively reduce the esophageal mucosal irritation symptoms induced by Lugol's chromoendoscopy.
作者 肖文 赵超
出处 《国外医学(消化系疾病分册)》 2005年第4期259-260,253,共3页
关键词 卢戈氏液染色 色素内镜 硫代硫酸钠 食管粘膜刺激症状 硫代硫酸钠溶液 刺激症状 食管粘膜 症状缓解 硫糖铝混悬液 不同程度 Lugol's stain Chromoendoscopy Sodium thiosulfate Esophageal mucosal irritation symptom
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