1El - Maarri D, Herbiniaux U, Walter J, et al. A rapid quantitative non - radioactive bisuifite- SnuPE - IP RP HPLC assay for methylation analysis at specific CpG sites [J] . Nucleic Acids Res. 2002, 30(6): e25.
2Eads CA, Danenberg KD, Kawakami K, etal. MethyLight: a highthroughput assay to measure DNA methylation [ J ] . Nucleic Acids Res. 2000, 28 (8): E32.
3Oefner Pi, Bonn GK, Huber CG, ct al. Comparative study of capillary zone electrophoresis and high - performance liquid chromatoguaphy in the analysis of oligonucleotides and DNA [J] .J Chromatogr. 1992,625 (2): 331 - 340.
5Banmer A, Wiedemann U, Hergersberg M, et al. A novel MSP - DHPLC method for the investigation of the methylation status of imprinted genes enables the molecular detection of low cell mosaicisms [ J ] .Hum Mutat. 2001, 17 (5): 423-430.
6Monk M. Epigenetic programming of differential gene in development and evolution [J] .DeGenet, 1995, 17 (3): 1882197.
7Tycko B. Epigenetic gene silencing in cancer [J] .J Clin Invest,2000, 105 (4): 4012407.
8Wu J, lssa J, Hermen J, et al. Expression of an exogenous eukaryotic DNA methyl transferase gene induces transformation of NIN3T3 ceils[J].Proc Natl Acad Sci USA, 1993, 90 (19): 8891-8895.
9Oakeley EJ, Schmitt F, Jost JP. Quantification of 5 - methylcytosine in DNA by the chloroacetaldehyde reaction [ J ] . Biotechniques, 1999,27 (4): 744 - 746.
10Wainfan E, Dizik M, Stender M, et al. Methyl group in carcinogenesis: effects on DNA methylation and gene expression [ J ] . Cancer Res. 1992, 52: 2071-2077.