快速酶联免疫吸附法检测血清脂阿拉伯甘露糖-IgG对肺结核的诊断价值

Detection of lipoarabinomannan-IgG in serum for the diagnosis of pulmonary tuberculosis

目的评估脂阿拉伯甘露糖-IgG(LAM-IgG)检测对活动性肺结核的诊断价值。方法采用快速酶联免疫吸附法(ELISA)检测90例肺结核、53例肺癌患者及30例正常人血清中的LAM-IgG。结果肺结核组LAM-IgG阳性率为82%,其中痰结核杆菌涂(+)培(+)组达96%,涂(—)培(—)组为69%:肺癌组4例阳性,正常组1例阳性。假阳性率分别为8%和3%。结论提示血清LAM-IgG测定是肺结核患者一项有用的辅助诊断手段。

Objective To ascertain the value of lipoarabinomannan-lgG (LAM-IgG) determination in the diagnosis of pulmonary tuberculosis. Medthod LAM-IgG in sera obtained from 90 patients with acitve pulmonary tuberculosis, 53 patients with lung cancer and 30 healthy individuals were detected by using rapid enzyme-linked immunosorbent assay (ELISA). Results The positive rate was 82% in tuberculosis group, and the false positive rates were 8% and 3% in cancer group and healthy controls respectively. Conclusion The results suggested that rapid ELISA for LAM-IgG detection was a useful supplementary tool for diagnosis of pulmonary tuberculosis.