SOD苹果对D-半乳糖所致衰老小鼠防御酶及脂质过氧化的影响

Influence of SOD-enriched Apple on Defensive Enzymes and Lipid Peroxidation of Mice Treated with D-galactose

以SOD,CAT,GSH_PX和MDA为指标,研究了SOD苹果对D_半乳糖所致衰老小鼠体内活性氧防御能力的影响.结果表明,饲喂SOD苹果可显著提高小鼠血清和心、肝组织的SOD,CAT和GSH_PX活性,抑制脂质过氧化作用,降低MDA含量.结果显示,SOD苹果可增强小鼠体内的抗氧化活性,因此有利于延迟其衰老进程.

Influence of SOD-enriched apple on defensive enzymes against active oxygen and lipid peroxidation of mice treated with D-galactose was studied by measuring activity of superoxide dismutase（SOD）, catalase（CAT）, glutathione peroxidase（GSH-PX） and content of malondialdehyde（MDA）. The results showed that feeding mice with SOD-enriched apple resulted in significant increases in activity of SOD, CAT and GSH-PX in serum, heart and liver tissue. Therefore, the content of MDA was markedly decreased compared with the control. It is suggested that supplementation of SOD-enriched apple in the feedstuff may enhance the ability of mice to scavenge the active oxygen and consequently, retard their aging process.