鼻咽癌患者放疗前后Lp(a)与NO水平的观察与分析

Observation and Analysis of Plasma Lp(a) and Serum NO in Patients with Nasopharyngeal Carcinoma

目的:测定鼻咽癌患者放疗前后血浆脂蛋白(a)和血清NO含量,探讨其水平变化的临床意义。方法:分别用单克隆抗体浊度法和Griess法测定了32例鼻咽癌患者和50例健康者的血浆脂蛋白(a)和NO的含量。结果:鼻咽癌患者放疗前的血浆脂蛋白(a)和NO水平较健康对照组增高差异有非常显著性(P<0.01),放疗后二者水平接近健康对照组。结论:血浆脂蛋白(a)和血清NO可能在鼻咽癌病变发展过程中发挥重要作用。

Objective To study changes and clinical significances of plasma Lp（a） and serum NO in patients with nasopharyngeal carcinoma. Methods Monoclonal antibody turbidimetry and Griess methods were used to detect the plasma Lp （a） and serum NO in 32 patients with nasopharyngeal carcinoma and 50 healthy persons. Results Plasma Lp（a） and serum NO in patients with nasopharyngeal carcinoma before therapy were higher than healthy persons （P〈0. 01 ）. And they were got closure to the control group after therapy. Conclusions Plasma Lp （a） and NO may play important roles in patients with nasopharyngeal carcinoma.