摘要
内源性哇巴因(EO)是近年发现的一种内循激素,本文主要从EO的生物学特性、受体与抗体、检测、EO与疾病及EO与血管内皮细胞等方面进行综述。
Endogenous ouabain (EO) is a recently found hormone that may be secreted from adrenal cortex. As an endogenous mammalian analogue of cardiac glycosides and an inhibitor of the sodium pump, it regulates the body fluid balance, urine sodium extraction and vasoconstrictive tone, and thus plays an important role in the pathogenesis of hypertension and some other cardiovascular disorders. This articke reviews its biological features, receptor and antibody, detection, effects on diseases and relationship with endothelial cells
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2005年第4期534-538,共5页
Acta Academiae Medicinae Sinicae
关键词
哇巴因
激素
高血压
ouabain
hormone
hypertension