精氨酸对阻塞性黄疸患者红细胞免疫功能的影响

Immuno-stimulatory effect of arginine on the red blood Cells immune function in patients with obstructive jaundice

通过检测阻塞性黄疸患者的红细胞C_3b受体酵母菌花环率(RCR)和红细胞免疫复合物酵母菌花环率(RICR),并观察精氨酸的免疫调节作用,结果发现阻塞性黄疸时红细胞免疫功能受损,而精氨酸能改善其红细胞免疫功能。因此,精氨酸作为一种免疫调节剂应用于临床,对阻塞性黄疸患者围手术期免疫功能的增强及其抗感染能力的提高具有一定的意义。

This study was designed to observe the changes of the red blood cell immune function in patients with obstructive jaundice and to study immunological effect of perioperitive arginine therapy. The results showed that the yeast-rosette rates of red blood cell C3b recep- tor (RCR) in patients with obstructive jaundice were significantly lower than normal controls. The yeast-rosette rates of red blood cell im- mune complex (VICR) were higher than those of normal controls. These indicated that after obstructive jaundice the red blood cell immune function was inhibited and the perioperative supplemented arginine enhanced the red blood cell immune function of patients with obstruc- tive jaundice. Arginine, as a known immuno- modulator, is very valuable for increasing the immune function of patients with obstructive jaundice.