扩冠冲剂对缺血性心脏病本虚标实证患者免疫功能的影响

Effects of Kuo Guan(扩冠)Powder on the Immunological Functions in Patients with Ben-Xu Biao-Shi Syndrome(本虚标实证)of Ischemic Heart Disease

17例缺血性心脏病气阳虚血瘀证、14例缺血性心脏病阴虚血瘀证患者分别经扩冠Ⅰ号冲剂(益气活血)及扩冠Ⅱ号冲剂(滋阴活血)治疗一个月,使患者增高的血清IgG、CIC、IC-IgG、IC-C_3、C_3、外周 B 细胞数量及 T_4/T_8比值明显降低;外周 OKT_3^+、OKT_4^+及 OKT_8^+细胞百分率显著升高。患者紊乱的免疫功能基本恢复正常,表明两种扩冠冲剂具有良好的免疫调节作用。

Ischemic heart disease(IHD)is correlated with the tmmunodisturbances,In this study,the immunological effects of Kuo Guan No 1,a powder for aiding Qi(气)and activating the blood,in 17 cases of Qi Yang Xu Xue Yu(QYXXY,气阳虚血瘀)syndrome,Kuo Guan No 2,powder for nourishing the Yin(阴)and activating the blood,in 14 cases of Yin-Xu Xue-Yu(YXXY,阴虚血瘀)syndrome had been observed in one month treatment. After treatment with both powder of Kuo Guan No 1 and Kuo Guan No 2,the increased levels of IgG,CIC,IC-IgG and IC-C_3 in serum and the numbers of B cells in peripheral blood lymphocyte (PBL)of the patients with Ben-Xu Biao-Shi(BXBS,)syndrome of IHD angina were markedly decreased and showed no significant difference while compared with the normal controls(P>0.05); the numbers of OKT_3^+,OKT_4^+ and OKT_8^+ cells in PBL,which were lower before treatment in both groups,were obviot,sly increased and showed no marked difference with the controls(P>0.05);the higher ratio of T_4/T_8 was lowered in group of YXXY syndrome,and showed no difference while compared with the controls(P>0.05),but the ratio in QYXXY syndrome group was lowered than that in the controls(P<0.05).After the treatment with Kuo Guan No 1,the increased level of C_3 in serum in QYXXY group was lowered down to that of the controls(P>0.05).The results indicated that it is reasonable to consider that'Kuo Guan'powder is an immunoregulative preparation for patients with BXBS syndrome of IHD angina.