电感耦合等离子体光谱法测定新疆奎屯氟砷中毒患者尿中的14种元素含量的研究

Determination of the Contents of Fourteen Elements in Urine of Xinjiang Kuitun Fluorine Poisoning and Arsenic-Fluoride Poisoning Patients by ICP-AES

建立一种用电感耦合等离子体光谱法测定氟中毒, 氟砷联合中毒患者尿中的K, Na, Ca, Mg, P, Zn, Al, Ba, Co, Cu, Ni, Sr, Cr, Ti 14种元素含量的方法. 研究了电感耦合等离子体光谱法的操作条件及各元素的检出限, 精密度和线性范围, 方法的相对标准偏差为0.24%～2.47%(n=10). 平均回收率为90.4%～100.5%. 与健康对照组比较, 氟中毒和氟砷联合中毒患者组尿中的K, Na的含量高于健康对照组;氟砷联合中毒患者尿液中的Ba, Co, Cu, Ni, Cr的含量比氟中毒组和对照组的要高, 具有统计学意义(P＜0.05). P, Ca, Mg, Zn, Al, Ti, Sr三组间比较无统计学意义(P＞0.05). 方法灵敏, 简单, 重现性好, 数据可靠.

A method of determining the contents of K, Na, Ca, Mg, P, Zn, Al, Ba, Co, Cu, Ni, Sr, Cr and Ti, fourteen elements, in urine of Xinjiang Kuitun fluorine poisoning and arsenic-fluoride poisoning patients was developed. The operation conditions of ICP- AES, and the lowest test concentration, precision and linear ranges were studied. The relative standard deviation of the method was 0.24% -2.47% （ n = 10）, the average recoveries were 90.4%-100.5%. The contents of K and Na in urine of fluorine poisoning and arsenic-fluoride poisoning patients were higher than those of healthy contrast group. The contents of Ba, Co, Cu, Ni and Cr in the urine of arsenic-fluoride poisoning patients were higher than those of fluorine poisoning patients and healthy contrast group（ P 〈 0.05）. The contents of P, Ca, Mg, Zn, Al, Sr and Ti do not have statistic significance（P〉0.05）. The method was sensitive, simple and accurate. The experiment data was reliable.