乙肝型炎肝硬化患者肝移植后近期肝肾脾功能的变化

Early changes of the hepatic renal and splenic function in hepatitis B liver cirrhosis patient after liver transplantation

目的:观察乙型肝炎肝硬化患者肝移植前后肝、肾及脾功能的变化。方法:行肝移植治疗的11例乙型肝炎肝硬化患者,移植前后检测肝、肾及脾功能,分析其变化。结果:凝血酶原时间:术后2d已显著低于术前,术后5d正常;球蛋白:术后1d正常,2d显著低于术前;肌酐:术后1d显著高于术前,7d恢复正常;血小板:术后3d显著下降,14d显著高于术前,21d正常。肾功能不全发生率72.3%,但均能恢复。结论:肝移植后,凝血酶原时间和球蛋白恢复正常,肌酐上升后短时间内可恢复正常,血小板下降后又恢复正常。

Objective ： To research the changes of the hepatic, renal and splenic function in hepatitis B liver cirrhosis patient after liver transplantation. Methods ：Liver transplantation is performed for 11 cases suffered from hepatitis B liver cirrhosis, the hepatic,renal and splenic functions are observed,their changes are analysed. Results ：Time of thrombin is lower significantly after operated 3 days than before operation and get to normal after operated 5 days;globin get to normal after operated 1 day and is lower significantly after operated 2days than before operated;Cr is higher significantly after operated 2 days than before operated and get to normal after operated 7 days;blood platelet is lower significantly after operated 3 days than before operated and higher significantly after operated 14 days than before operated,get to normal after operated 21 days. Conclusion ：After liver transplantation,time of thrombin and glcbin get to normal,Cr rises up at the first and get to normal then,blood platelet decreases at the first and get to normal then.