罗布麻茶抗衰老、高血压及高血脂作用的观察

Observation on Anti-Aging,Antihypertensive and Antihyperlipemic Effect of Apocynum venetum Leaf Extract

用罗布麻茶治疗高血压病患者60例,治疗前后比较,血压均值下降,P<0.01。治疗高脂血症患者40例,治疗前后比较,高密度脂蛋白上升,P<0.01。治疗组服药后额部立、卧时 RP 时间间期差值(⊿RPF)自10.1±6.0延长至15.3±7.3ms,P<0.01,显示罗布麻茶对改善心血管功能有一定的作用。治疗组服药后红细胞超氧化物歧化酶(SOD)值从治前546.1±51.0增至574.6±42.0μg/g Hb,P<0.05。另外,本药可延缓细胞核随培养时间延长而增大的倾向,并使胚肺二倍体纤维母细胞传代次数从77代延至80代,显示有抗衰老作用。

The effect of Apocynum venetum leaf extract on hypertension,hyperlipemia,SOD content of erythrocyte,platelet aggregation rate,pulse wave transmission time(RP interval)and human diploid cell was studied to evaluate if it has some anti-aging effects.The mean BP in 60 cases of the treated group decreased from 171±19/98±11 mmHg to 154±22/91±10 mmHg and 148±17/89±10 mmHg after treatment for 4 and 8 weeks(P<0.01).The HDL-C in 40 cases of hyperlipemia increased from 47.5±13 mg% to 63.9±18 mg%(P<0.01).These.results were better than those in the control groups. △RP_F was lengthened from 10.1±6.0 ms to 15.3±7.3 ms,which indicated that the cardiac perfor- mance was improved.No significant change of platelet aggregation rate was obtained after 5～8 weeks treatment.The retarding effect on cell aging was observed by the morphologic changes of nucleus and the increase of subcuttivation from 77 to 80 generations.SOD content of erythrocyte was significantly increased from 546.1±51 μg/gHb to 574.6±42μg/gHb in 20 cases.So Apocynum venetum leaf extract might have some anti-aging effects.