摘要
目的探讨一种从切片图像反求建模的方法,并对人皮质骨微管道三维结构行形态观察.方法采用人桡骨中段为研究对象,经过预处理、脱水、包埋,利用连续切片技术,经图像处理反求建模法重构人桡骨中段的三维显微模型.对三维模型进行测量、推算,得到哈佛氏管走向、长度等数据.结果用此种方法建模得到的三维显微结构,真实地反映了人桡骨的骨内微结构.形态观察得出哈佛氏管在远离连通处夹角较小,平均为5.7°.在连通处附近(400～800μm),平均夹角为12.2°.结论重构骨三维显微结构,得到哈佛氏管的空间特征,为给人工活性骨的设计提供模型,进而指导人工活性骨的设计与制造.
Objective To establish a method of reverse engineering（RE） from microscopic images to describe the configuration of three -dimensions （3D）model. Methods Middle part diaphysis of human radius was chosen and pretreated with dehydration and embed for constructing three -dimension（ 3 D）microscopic model. The orientation and length of Haversian canals and the connection are measured and calculated. Results The three - dimension（3D） microscopic model reconstructed by microscopic images objectively reflected the real radius figure and based on that we conclude that the angle of two Haversian canals is small when it is away from the joint at average 5.7° when it around the joint（400 - 800μm） and average angle is 12.2° . Conclusion We can draw the spatial configuration of Haversian canals with the three - dimension（ 3 D） microscopic model and this could provide us a base to and instruct to make artificial bone.
出处
《中国骨肿瘤骨病》
2005年第2期87-90,共4页
Chinse Journal Of Bone Tumor And Bone Disease
基金
国家自然科学基金资助(50235020)
