红花注射液对动静脉内瘘成形术的影响

The chinical study of the effects of safflower injection on the patients received arteriovenous fistula operation.

目的探讨红花对动静脉内瘘术围手术期的影响。方法选用上海中医药大学曙光医院子2003年7月～2004年12月56例尿毒症患者,观察红花组和对照组在血液流变学,内瘘成熟后的血流量,及初次使用时间的变化。结果红花组治疗后的全血粘度下的高切变率,低切变率,改善程度明显优于对照组(P<0.05),同时内瘘血流量及内瘘初次使用时间也优于对照组(P<0.05)。结论红花注射液是预防动静脉内瘘术后血液高凝状态的有效药物,具有一定的临床应用价值。

Objective To study the effects of safflower injection after arteriovenous fistula operation. Methods Fifty six patients were randomly divided into two groups, The clinical therapeutic effects in the two groups were observed, including the effects on hemorheology, blood flow after fistula maturation and the first using time. Results After treatment, in the safflower injection group, the high-and low-shear whole blood viscosity lowered, significantly as compared with that in the control group （P〈0.05）. The blood flow after fistula maturation and the first use were better than that in the control group （P〈0.05）.Conclusion Safflower injection is effective for treating hypercoagulation status after creation of arteriovenous fistula, and is worthy of clinical application.