新疆克拉玛依地区抽样人群中胆囊结石危险因素流行病学研究

An epidemiological survey of gallstone in Kelamay region people

目的了解新疆克拉玛依地区胆囊结石流行病学的特点。方法依据该地区人口学资料,计划调查8257人,按规模大小成比例概率抽样(PPS)的方法随机抽样以确定抽样人群。对象均接受入户问卷调查及物理查体,同时预约行胆囊B超和空腹血糖血脂检查。SPSS11.0软件进行统计学处理,Logistic回归分析得出危险因素。结果调查的应答率为92.4%。胆石症患病率为15.45%。在众多危险因素中,贡献最大的依次为性别、胆总管内径和民族(OR值分别为1.92,1.83,1.4)。结论胆结石的形成是多因素作用的结果,其中性别、民族差异和胆总管内径对胆结石形成有一定的影响。

Objective To survey the etiology of gallstone disease in Kelamay region of Xinjiang. Methods A population of 8257 people based on local demographic data was chosen by means of PPS （Probability proportional to size）randomly. They were investigated by questionaire and physical examination, followed by ultrasound and analysis of fasting blood sugar and lipid profile. The data were analyzed by statistical software SPSS 11.0, and the main risk factors were identified by means of logistic regression. Results 92.4% of the designed population went through all the processes of the study. The prevalence of gallstone in Kelamay region was 15. 45 %. Among a variety of risk factors, the predominant ones were sex, diameter of the common bile duct and difference in nationality （ with OR = 1.92 , 1. 83 , 1.4 respectively ） . Conclusions The formation of gallstone is a result of the action of muhiple factors, among which, sex, difference of nationality and internal diameter of common bile duct have influence on its formation.