反相液相色谱法测定去甲氨噻肟酸乙酯的含量

Determination of Ethyl 2-(2-Aminothiazole-4-yl)-2-hydroxyiminoAcetate by Reversed-phase HPLC

用反相C18色谱柱,采用离子对色谱法,测定去甲氨噻肟酸乙酯的含量。本方法以溴化四丁基铵为离子对试剂,磷酸盐溶液为缓冲溶液,乙睛和水组成流动相。

Ion - pair chromatography was applied aminothiazole- 4 - yl） - 2 - hydroxyimino acetate phase consist of acetonitrile and water, using butyl - using phosphate asbuffer solution. to determine the content of ethyl 2 - （2 - , using areversed phase Cls column. The mobile - tetra ammonium bromide as ion - pair reagent,