特发性黄斑前膜手术疗效分析

Evaluate about the efficiency of the idiopathic macular membrane surgery

目的探讨特发性黄斑前膜手术治疗的效果及安全性。方法特发性黄斑前膜21眼行玻璃体手术,术后1、3、6及12月,进行视力、光学相干断层成像(opticalcoherencetomography,OCT)、多焦视网膜电流图(multifocalelectroretinogram,MERG)检查,应用SPSS11.5软件对结果进行统计学分析。结果(1)术后12月视力改善2行以上90%(19/21),视物变形改善81%(17/21),与术前差异有显著性(P<0.05);(2)OCT显示手术前视网膜平均厚度496.76±93ìm,术后12月平均厚度(176.09±27.97)ìm,与术前差异有显著性(P<0.05);(3)术前MERG地形图可见中心峰下降,一级反应1、2、环P1波反应密度明显降低,术后12月MERG中央峰逐渐恢复,1、2、环P1波反应密度明显升高,与术前差异有显著性(P<0.05)。结论玻璃体手术治疗特发性黄斑前膜疗效可靠,视力、OCT及MERG可以较好地进行疗效客观评价。

Objective To evaluate the safety and efficacy of idiopathic macular membrane surgery. Methods 21 eyes of 21 patients with idiopathic macular membrane who underwent vitrectomy were studied. Visual acuity,optical coherence tomography （OCT） and multifocal electroretinogram （MERG） were examined preoperatively and 1, 3, 6, and 12 month postoperatively. The results were analyzed statistically by SPSS 11.5. Results （ 1 ） 12month after surgery, those whose visual acuity elevation was more than 2 line accounted for 90.5% （ 19/21 ） and those whose visual distortion was improved accounted for about 81% （17/21） （P〈0.05）; （2） OCT showed that the average retina thickness was （496.76 ± 93）μm n preoperatively and （176.09 ± 27.97）μm postoperatively, the difference was significant statistically （ P〈0.05 ）; （3） The MERG central peaks were lower and the response densities of wave P1 of ring 1 and ring 2 were lower before the operation while obviously higher after the operation （P〈0.05）. Conclusion The efficiency of vitreous surgery on treatment of idiopathic macular membrane is obvious, and can be evaluated by the visual acuity, OCT and MERG.