树舌(Ganoderma lipsiense)化学成分及药理学研究进展

A Review of Researches on Chemical Composition and Pharmacology of Ganoderma lipsiense(Batsch)G.F. Atk

树舌的化学成分包括多糖、甾体化合物、三萜、脂类、氨基酸、多肽、蛋白质类、生物碱类、酚类、内酯、香豆素类和甙类以及微量元素等。树舌具有广泛的药理活性,主要包括调节机体免疫系统、抗肿瘤、抗病毒、消炎抗菌、降血糖、调节血压、阻碍血小板凝集和强心作用。临床用于治疗腹水癌、神经系统疾病、肝炎、心脏病、糖尿病和糖尿病并发症,预防和治疗胃溃疡、急慢性胃炎、十二指肠溃疡、胃酸过多等胃病,具有较高的药用价值。本文对树舌的化学成分、药理作用及临床应用情况进行了综述。

The chemical compositions in Ganoderma lipsiense （Batsch） G. F. Atk are polysaccharide, steroid, triterpenes, lipids, amino acids, polypeptide, protein, alkaloids, phenol, lactone, coumarin, glycosides and microelements. Comparatively comprehensive pharmacological effects are found in G. lipsiense, which mainly contain actions such as modulating immune system of body, inhibiting tumor and virus, eliminating inflammation, reducing blood sugar, modulating blood pressure, and counteracting the coagulation of blood platelet and cardiotonic. G. lipsicnse is clinicly used to remedy ascites carcinoma, nervous system diseases, hepatitis, heart diseases, diabetes and diabetic complications, to prevent and cure diseases of gastric ulcer, acute gastritis, chronic gastritis, duodenal bulbar ulcer and hyperhydrochloric. Its officinal merit is better. Recent research development of chemical composition, pharmacological effect and clinical application of G. lipsiense is reviewed in this article.