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保湿剂并用糖皮质激素治疗异位性皮炎的疗效观察 被引量:5

Effects of steroid plus a moisturizer regimen in the treatment of atopic dermatitis
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摘要 目的:研究保湿剂对外用糖皮质激素治疗异位性皮炎疗效的影响。方法:通过随机对照临床研究,采用湿疹面积及严重度指数评分法,对外用糖皮质激素和保湿剂治疗45例轻中度异位性皮炎患者的临床疗效进行评估。结果:与单独外用糖皮质激素或保湿剂相比,联合外用糖皮质激素加保湿剂治疗轻、中度异位性皮炎,较单用糖皮质激素疗效显著,单独外用保湿剂可明显减轻轻中度异位性皮炎患者的临床症状。结论:外用保湿剂能增强局部糖皮质激素的疗效,单独外用保湿剂治疗异位性皮炎可获得与糖皮质激素相近的疗效。 Objective: To evaluate the effects of adding a moisturizer to steroid cream regimen in the treatment of atopic dermatitis. Methods: The controlled, randomized study was undertaken to compare applications of steroid cream plus moisturizer with application of steroid or moisturizing cream alone by eczema area and severity index scores. Results: Combination of steroid cream and moisturizer created additional statistically significant improvement in clinical scores. Topical steroid or moisturizer alone produced statistically significantly improvement in clinical scores. Conclusion: Combination of steroid cream and moisturizer can increase the steroid effect in the treatment of atopic dermatitis. Application of moisturizer alone had approximate effect with topical steroid in the treatment of atopic dermatitis.
出处 《中国麻风皮肤病杂志》 2005年第9期704-705,共2页 China Journal of Leprosy and Skin Diseases
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  • 1Rippke F, Schreiner V, Doering T, et al. Stratum comeum pH in atopic dermatitis: impact on S barrier function and colonization with staphylococcu aureus. Am J Clin Dermatol 2004 ; 5 : 217 - 223.
  • 2Roll A, Cozzio A, Fischer B, et al. Microbial colonization and atopic dermatitis. Curt Opin Mlergy Clin Immonol 2004: 4:373 - 378.
  • 3Hanifin JM, Thurston M, Omoto M, et al. The eczema area and severityindex( EASI): assessment of reliability in atopic dermatitis. EASI evaluator Group. Exp Dermatol 2001 ; 10: 11 - 18.
  • 4Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Vemereol (Stockh) 1980; (Suppl) 92 : 44 - 47.
  • 5Loden M, Andersson AC, Andersson C, et al. Instrumental dermatologist evaluation of the effect of glycerin and urea on dry skin in atopic dermatitis. Skin Res Technol 2001 ;7:209- 213.
  • 6Hanifin JM, Hebert AA, Mays SR, et al. Effects of a low - potency corticosteroid lotion plus a moisturizing regimen in the treatment of atopic dermatitis. Curt Therapeu Res 1998;59:227- 233.
  • 7LodenM, Andersson AC, Lindberg M. Improvement in skin barrier function in patients with atopic dermatitis after treatment with a moisturizing cream. Br J Dermatol 1999; 140:264- 267.
  • 8Marie L. The skin barrier and use of moisturizers in atopic dermatitis. Clinics in Dermatology 2003;21 : 145 - 157.

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