肛门部疾病所致肛周湿疹的综合治疗疗效观察

Efficacy of comprehensive treatments for the perianal eczema caused by the anal diseases

目的:观察药物和手术综合治疗痔、肛裂、肛瘘、脱肛等所致肛门松弛引起的肛周湿疹的疗效。方法:120例肛周湿疹患者随机分为3组,A组:单纯药物改善肛周皮损(包括中药熏洗、外用药膏等);B组:单纯手术治疗引起肛周湿疹的肛门部疾病;A+B组:药物改善肛周皮损后再手术治疗原发病。治疗时间为4周。结果:3组患者的治愈率分别为22.50%、32.50%和57.50%;有效率分别为40.00%、52.50%和85.00%。3组患者的疗效不同(P<0.01)。组间比较:A+B组疗效优于A组及B组(P<0.05)。而A组与B组之间的疗效,差异无显著统计学意义(P>0.05)。结论:药物和手术综合治疗痔、肛裂、肛瘘和脱肛等原因所致肛门松弛而引起的肛周湿疹,疗效确切,不易复发。

Objective： To evaluate the efficacy of comprehensive treatments including medicine and operation for the perianal eczema which is caused by the anal disease such as haemorrhoids, fissures, fistulas and so on. Methotis： A randomized conrad clinical study was carried out. 120 patients with perianal eczema were divided into three groups and treated for four weeks. Group A was treated with medicine including traditional Chinese medicine and ointment for the improvement of the perianal skin. Group B was treated with operation for the mini disease which caused the perianal eczema. Group A ＋ B was treated with medicine for the improvement of the perianal skin first, then treated with operation for the causes. Results： The cure rate was 22.50% for group A, 32.50% for group B and 57.50% for group A ＋ B. The response rate was 40.00%, 52.50% and 85.00%, respectively. In comparison between three groups the therapeutic effect was different. There was a significantly statistical difference between Group A ＋ B and Group B （ P 〈 0.05）, and no significantly statistical difference between Group A and Group B（ P 〉 0.05） in the efficacy. Conclusion： Comprehensive treatment including medicine and operation is definitely effective to the perianal eczema which is caused by the anal diseases such as haemorrhoids, fissures, fistula and so on.