摘要
①目的研究颈椎前路手术咽喉部并发症的发生率和甲基泼尼松龙对其的防治作用.②方法颈椎前路手术病人88例,随机分成两组:A组46例作为对照组;B组42例,分别在术前、术后12和24 h静注甲基泼尼松龙0.5 mg/kg.在术前和术后24～36 h行咽喉部检查,并记录病人的主观症状.③结果 A、B组术后咽喉部检查出现异常者分别为42例(91.3%)和23例(54.8%),差异有显著性(χ2=8.36,P<0.01);出现主观症状者A组36例,B组16例,两组比较差异也有显著性(χ2=7.52,P<0.01).A组的咽喉部损伤和水肿程度较B组更为严重(u=3.84,P<0.01).④结论颈椎前路手术前进行咽喉部系统检查是必要的,使用甲基泼尼松龙可明显减少颈椎前路手术咽喉部并发症的发生.
Objective To investigate the incidence of laryngopharynx complications in patients undergoing cervical spine surgery through the anterior approach and to evaluate the effects of methylprednisolone （Mp） for prevention of the morbidity. Methods Eighty-eight patients undergoing the operation were divided into two groups： group A （control group, n = 46）, and group B （n=42）. Those in group B received 0.5 mg/kg Mp intravenously at the end of the operation as well as 12 h and 24 h later. All of them underwent examination of laryngopharynx on the day before and 24-36 h after the operation. The subjective symptoms were recorded. Results The laryngopharynx examination was abnormal in 42 （91. 3%） patients in group A and 23 （54.8%） in group B, postoperatively X^2= 8.36, P〈0.01）, and 36 and 16 patients reported subjective symptoms in groups A and B, respectively X^2 =7.52, P〈0.01）. The lesions observed were more severe in group A （u= 3. 84, P〈0. 01）. Conclusion Systematic laryngopharynx examination is necessary before the operation and laryngopharynx complications of anterior-approach cervical spinal surgery can be decreased by administration of methylprednisolone.
出处
《齐鲁医学杂志》
2005年第5期427-428,共2页
Medical Journal of Qilu
关键词
颈椎
并发症
咽
喉
甲基泼尼松龙
cervical vertebrae
cornplications
pharynx
larynx
methylprednisolone
