Synthesis and Biological Evaluation of Pyranone Analogues of Territrem B
Synthesis and Biological Evaluation of Pyranone Analogues of Territrem B
摘要
23 compounds containing pyranone pharmacophore of territrem B were designed and synthesized. Some of the analogues showed IC50 values of AChE inhibition at 10^-5 mol/L.
23 compounds containing pyranone pharmacophore of territrem B were designed and synthesized. Some of the analogues showed IC50 values of AChE inhibition at 10^-5 mol/L.
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