XPC基因功能变异与肿瘤发生
被引量:3
Variation of XPC gene and carcinogenesis
摘要
着色性干皮病基因组C(XPC)是DNA损伤识别因子,启动DNA修复功能,从而维持细胞的遗传稳定性。DNA修复功能与肿瘤的发生及高异质性有关。现介绍XPC的生物学特性、多态性以及XPC与核苷酸切除修复(NER)、肿瘤发生、细胞周期调节的关系。
出处
《国外医学(肿瘤学分册)》
2005年第8期576-579,共4页
Foreign Medical Sciences (Cancer Section)
基金
国家自然科学基金主任基金项目(30340057)
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