期刊文献+

细胞周期素D1与肺癌研究进展

Advances of researches on Cyclin D1 and lung cancer
下载PDF
导出
摘要 细胞周期素Dl(CyclinDl)在细胞周期的正常调控中起着关键作用。近期研究发现, 在肺癌发病过程中CyclinDl基因表达失衡有不同的分子生物学机制,其表达增高的部位、水平、和方式均有重要特点。现综述CyclinDl与肺癌研究的最新进展。
出处 《国外医学(肿瘤学分册)》 2005年第8期603-605,共3页 Foreign Medical Sciences (Cancer Section)
  • 相关文献

参考文献16

  • 1Sherr CJ. Cancer cell cycles. Science, 1996,274(2) :1672-1676.
  • 2Belaud Rotureau MA, Parrens M, Dubus P, er al. A comparative analysis of FISH, RT- PCR, PCR, and immunohistochemistry for the diagnosis of mantle cell lymphomas. Mod Pathol,2002,15 (5) :517-525.
  • 3Holley SL, Parkes G, Matthias C, et al. Cyclin D1 polymophism and expression in patients with squamous cell carcinoma of the head and neck. Am J Pathol,2001,159 ( 5 ): 1917-1924.
  • 4Zhang YJ,Chen SY, Chen CJ,et al. Polymorhisms in cyclin D1 gene and hepatocellular carcinoma. Mol Carcinog, 2002,33 ( 2 ): 125-129.
  • 5Jin M,Inoue S,Umermura T,et al. Cyclin D1 ,p16 and retinoblastoma gene product expression as a predictor for prognosis in non smallcell lung cancer at stages Ⅰ and Ⅱ. Lung Cancer, 2001,34(2) :207-218.
  • 6Watters AD, Latif Z, Forsyth A, et al. Genetic aberrations of c-myc and CCND1 in the development of bladder cancer. Br J Cancer,2002,87(6) :654-658.
  • 7Han S, Sidell N, Roman J. Fibronectin stimulates human lung carcinoma cell proliferation by suppressing p21 gene expression via signals involving Erk and Rho kinase. Cancer Lett, 2005,219( 1 ) :71-81.
  • 8Betticher DC, Heighway J, Hasleton PS, et al. Prognostic significance of CCND1 (cyclin D1 ) overexpression in ptimary resected non-smallcell lung cancer. Br J Cancer, 1996,73 (3) :294-300.
  • 9Brambilla E, Gazzeri S, Moro D, et al : Alteration of Rb pathway ( Rbp16INK4-cyclin D1 ) in preinvasive bronchial lesions. Clin Cancer Res, 1999,5(2) :243-250.
  • 10Ratschiller D,Heighway J,Gugger M,et al. Cyclin D1 overexperssion in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival. J Clinical Oncology,2003,21 ( 11 ):2085-2093.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部