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树突状细胞促成熟因子研究进展 被引量:1

Progress in maturation-promoting factor of dendritic cells
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摘要 树突状细胞(DC)是体内抗原递呈功能最强、惟一能激活幼稚T淋巴细胞的专职抗原递呈细胞,在肿瘤免疫中的作用日益受到重视。目前临床所用的DC多是从外周血单个核细胞经体外培养而来。体外培养第一阶段的方法已得到公认即GM-CSF+TL-4,由此得到不成熟DC。第二阶段即用不同促成熟因子作用于不成熟DC,使之成熟。目前促成熟因子种类繁多,效果亦众说纷纭。现就常用的促成熟因子的作用机制及其效果作一综述。
出处 《国外医学(肿瘤学分册)》 2005年第9期646-649,共4页 Foreign Medical Sciences (Cancer Section)
基金 江苏省卫生厅医学科技发展重大课题基金资助项目(H200211)
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参考文献20

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共引文献11

同被引文献24

  • 1刘宁.树突状细胞的研究进展[J].国际医药卫生导报,2006,12(6):121-123. 被引量:5
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