直肠黏膜保护剂在先天性肛门直肠闭锁肛门成形术后的应用

Application of Rectal Mucosa Protective Agent after Anoplasty in Treatment of Cogenitai Anorectai Atresia

观察先天性直肠肛门闭锁肛门成形术后直肠黏膜保护剂对创缘愈合的作用，选择先天性直肠肛门闭锁52例，于肛门成形术后给予直肠黏膜保护剂治疗（研究组），与没有应用直肠黏膜保护剂的59例（对照组）进行比较。研究组术后创缘感染率为9．3％，创缘渗液的平均消失时间为3．3d，水肿消退的平均时间为4．2d．而对照组分别为17．0％、5．0d、6，6d，各项指标差异具有统计学意义。结果显示，直肠黏膜保护剂对先天性直肠肛门闭锁肛门成形术后创缘的愈合具有促进作用。

The objective of this study was to evaluate the healing effect of rectal mucosa protective agent （RMPA） on the surgical wound after anoplasty in the treatment of cogenital anorectal atresia （CAA）. Fifty two cases with CAA who underwent anoplasty received RMPA （group A） and fifty nine cases with CAA who underwent anoplasty did not received RMPA （group B）. As results, the postoperative wound infection rate was 9.3%,the mean wound exudating stoping period of time was 3.3 days, and the mean edema disappear period of time was 4.2 days in group A, while that in group B was 17.0% ,5 days and 8.6 days respectively. The differences of all the indexes had statistical significance. It is suggested that RMPA is of the promoting effect on wound healing after anoplasty in the treatment of CAA.