聚明胶肽用于纠正低血容量休克的临床研究

Clinic Effect of Polygeline on the Hypovolemic Shock

目的:研究聚明胶肽应用于低血容量休克的扩容效果。方法:选择预计失血量在5%和20%之间的病人60例,随机均分为两组,分别输入等量的聚明胶肽和贺斯,全身麻醉后监测 BP、P、ECG、CVP 以及离子和血红蛋白、压积在手术前后的变化以比较聚明胶肽和贺斯的扩容和维持内环境稳定的效果。结果:两组病人在血压、脉搏、中心静脉压、离子以及血红蛋白和压积方面的变化均无明显统计学差异。结论:聚明胶肽具有明显的纠正低血容量、扩容和维持内环境稳定的作用,与羟乙基淀粉类作用相似。

Objective： To investigate the effect of polygeline on the hypovolemic shock.Methods： 60 patients were allocated into two groups, polygeline group and haes group.Blood loss in all patients is between 5 percent and 20 percent.Such monitoring methods as： blood pressure, pace, electrocardiogram, central venous pressure and blood anion, were used in operation.Also the hemoglobin and hematocart were detected.Results： There were no differences on blood pressure, pace, central venous pressure, blood anion, hemoglobin and bematocrat, in two groups at all.Conclusion： Polygeline could correct hypovolemia and maintain internal environment stability. It has just the same effect as hydroxyethyl starch.