摘要
Nowadays, liver metastasis remains difficult to cure. When tumor cells escape and arrive in the liver sinusoids, they encounter the local defense mechanism specific to the liver. The sinusoidal cells have been widely described in physiologic conditions and in relation to metastasis during the past 30 years. This paper provides an 'overview' of how these cells function in health and in diseases such as liver metastasis.
Nowadays, liver metastasis remains difficult to cure. When tumor cells escape and arrive in the liver sinusoids, they encounter the local defense mechanism specific to the liver. The sinusoidal cells have been widely described in physiologic conditions and in relation to metastasis during the past 30 years. This paper provides an “overview” of how these cells function in health and in diseases such as
基金
Supported by the Fund for Scientific Research-Flanders, No. 1.5.001.04N[F.B.]
关键词
肝窦状细胞
肝功能
结肠癌
肿瘤转移
Metastasis
Liver
Colon carcinoma
Sinusoidalcells
Kupffer cells
Liver sinusoidal endothelial cells
Hepatic NK cells
