期刊文献+

未成熟卵母细胞体外成熟影响因素的探讨 被引量:1

下载PDF
导出
摘要 随着人类辅助生殖技术(ART)的发展,人未成熟卵母细胞体外培养成熟(IVM)技术作为ART的有效改良,已成功应用于治疗不孕症,成为当代生殖医学的研究热点。IVM技术不仅可以避免药物诱发排卵带来的诸多弊端而且大大缩短了患者的就医时间,降低医疗费用,减少并发症。IVM技术虽已取得了一定的成就,但仍存在一些问题,有待于进一步完善。根据近4年的有关文献对未成熟卵母细胞的采集方法、IVM体外培养的影响因素、IVM存在的问题及IVM的临床应用与展望做一综述。
作者 梁莹 高颖
出处 《国外医学(计划生育分册)》 2005年第5期245-248,共4页
  • 相关文献

参考文献20

  • 1Patsouls E, Loutradis D, Drakakis P, et al. Messenger RNA expression for the follicle-stimulation hormone receptor and luteinizing hormone receptor in human oocytes and preimplantation-stage embryos.Fertil Steril, 2003, 79(5): 1187-1193.
  • 2Schoevers E J, Kidson A, Verheijen JH, et al. Effect of follicle-stimulating hormone on nuclear and cytoplasmic maturation of sow oocytes in vitro. Theriogenology,2003, 59(9): 2017-2028.
  • 3Roberts R, Iatropoulou A, Ciantar D, et al. Follicle-stimulating hormone affects metaphase I chromosome alignment and increases aneuploidy in mouse oocytes matured in vitro. Biol Reprod, 2005, 72(1): 107-118.
  • 4Liu HC, He Z, Rosenwarks Z. In vitro culture and in vitro maturation of mouse preantral follicles with recombinant gonadotropins. Fertil Steril, 2002, 77(2): 373-383.
  • 5Bevers MM, lzadyar F. Role of growth hormone and growth hormone receptor in oocyte meturation. Mol Cell Endocrinol, 2002, 197(1-2):173-178.
  • 6Kolle S, Stojkovic M, Boie G, et al. Growth hormone-related effects on anptosis, mitosis, and expression of connexin 43 in bovine in vitro maturation cumulus-oocyte complexes. Biol Reprod, 2003, 68 (5):1584-1589.
  • 7Oyamada T, Iwayama H, Fukui Y. Additional effect of epidermal of epidermal growth factor during in vitro maturation for individual bovine oocytes using a chemically defined medium. Zygote, 2004, 12(2): 143-150.
  • 8Abbas MM, Evans JJ, Sin IL, et al. Vascular endothelial growth factor and leptin: regulation in human cumulus cells and in flooicles. Acta Obstet Gynecol Scand, 2003, 82(11): 997-1003.
  • 9Luo H, Kimura K, Aoki M, et al. Effect of vascular endothelial growth factor on maturation, fertilization and developmental competence of bovine oocytes. J Vet Med Sci, 2002, 64(9): 803-806.
  • 10Kawano Y, Zeineh Hasan K, Fukuda J, et al. Production of vascular endothelial trowth factor and angiogenic factor in human follicular fluid. Mol Cell Endocrinol, 2003, 202(1-2): 19-23.

同被引文献31

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部