Rh阴性受者接受Rh阳性供肾移植三例

Rh-negative patients receiving Rh-positive renal grafts (3 cases report)

目的探讨Rh阴性尿毒症患者接受Rh阳性供肾移植的可行性及疗效。方法3例Rh阴性尿毒症患者接受Rh阳性供肾,术后定期随访,观察疗效。结果1例术后5年移植肾功能丧失;另2例已分别存活22个月及2个月,肾功能良好,抗Rh抗体为阴性。结论Rh阳性供肾经过充分灌洗,可移植给Rh阴性的尿毒症患者,短期效果良好,长期效果需继续观察。

Objective To investigate the effectiveness of Rh-negative patients receiving Rh-positive renal grafts. Methods Three Rh-positive kidneys were transplanted in 3 Rh-negative uremia patients respectively. The pre- and intraoperative conditions were evaluated. All patients were regularly followed up. Results Dysfunction occurred in one graft kidney 5 years after the operation, and the patient died of cardiovascular complication 8 years after the operation. The remaining 2 patients have survived 22 and 2 months respectively with normal renal function, and their Rh antibodies were negative 21 and 2 months after the operation respectively. Conclusion Fully perfused Rh-positive renal grafts can be transplanted to Rh-negative uremia patients. The short-term effect is satisfactory.