摘要
目的监测基层医院葡萄球菌的耐药现状,以指导临床医师正确选用抗生素。方法用纸片扩散法(K-B法)对189株葡萄球菌进行药敏试验,耐甲氧西林葡萄球菌(MRS)的检测,按美国临床实验室标准化委员会(NCCLS)1999年版进行。结果耐甲氧西林金黄色葡萄球菌(MRSA)检出率为29.9%;耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)检出率为31.3%;MRSA和MACNS对8种常用抗菌药物的耐药率均明显高于甲氧西林敏感葡萄球菌(MSS)。结论MRSA和MRCNS检出率不断升高,临床应重视耐药菌的检测与报告,及时有效地监测医院感染的发生与流行。
OBJECTIVE To supervise drug resistance status of Staphylococcus in montane hospital and offer scientific basis for reasonable usage of antibiotics. METHODS K-B method was used to determine the drug susceptibility of 189 isolates, and meticillin resistance was analyzed according to NCCLS （1999）. RESULTS Among 189 strains, meticillin-resistant S. aureus （MRSA）, meticillin-resistant coagulase-negative S. aureus （MRCNS） rated with 29. 9% and 31.3%, respectively. MRSA and MRCNS showed significant higher drug resistance than meticillin-sensitive Staphylococcus （MSS）. CONCLUSIONS The ratio of MRSA and MRCNS increases gradually. Rational use of antibiotics should be carried out according to reporting of drug-resistance, and it is important to supervise nosocomial infection efficiently.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2005年第9期1056-1057,共2页
Chinese Journal of Nosocomiology
关键词
葡萄球菌
医院感染
耐药性
Staphylococcus
Nosocomial infection
Drug resistance
