摘要
用胶束荧光法监测小蘖碱的血药浓度庞志功,汪宝琪,姜洪涛(西安医科大学药学系710061)关键词胶束荧光法,小蘖碱,血药浓度小蘖碱(berbeerine)是秦巴山区广为分布的中药材三棵针中所含季铵类生物碱中的主要成分之一[1],临床多用其盐酸盐治疗胃肠...
Berberine is a kind of fluorescent substance,one of main alkaloids in berberis wilsonae hemsl.SLS is used as micella reagent in aqueous medium.Using micella to improve sensitivity, we can determine micro or trace berberine exactly. We obtained C_(peak) is 2. 52 × 10 ̄(-5)mL,T_(peak) is 3h, 24 hours later, remnant is 9.1×10 ̄(-7)g/mL,respectively.The results indicate that berberine is a kind of natural antiinfection drug which posessess fast reaction, metaining long effective time and keeping high effective concentration.
出处
《化学研究与应用》
CAS
CSCD
1996年第2期286-288,共3页
Chemical Research and Application
关键词
荧光法
小蘖碱
血药浓度
micella fluoromery,berberine,blood-drug,concentration