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实验性胰腺癌动物模型研究进展 被引量:6

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摘要 从上世纪70年代用化学方法诱导制作出胰腺癌动物模型以来,经过数十年的发展,各国学者又设计出了多种胰腺癌动物模型并对其进行了大量的实验研究.上世纪90年代的裸鼠移植瘤模型,尤其是通过外科原位移植(SOI)组织学完整的瘤组织建立的"种植鼠"模型,和近年的基因工程模型,是更为接近人体肿瘤特征的动物模型.现将有关研究进展介绍如下.
出处 《胰腺病学》 2005年第3期187-189,共3页 Chinese JOurnal of Pancreatology
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  • 1Rinderknecht H, Haberfelde G, Maset R, et al. Pancreatic secretory abnormalities precede appearance of tumors of the pancreas in hamsters treated with bis-(2-oxopropyl)-N-nitrosamine. Dig Dis Sci, 1983, 28:526-538.
  • 2Takahashi M, Furukawa F, Toyoda K, et al. Effects of various prostaglandin synthesis inhibitors on pancreatic carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine. Carcinogenesis, 1990,11:393-395.
  • 3Wenger FA, Kilian M, Mautsch I, et al. Influence of octreotide on liver metastasis and heptic lipid peroxdation in BOP-induced pancreatic cancer in Syrian hamsters. Pancreas,2001,23:266-272.
  • 4Wenger FA, Kilian M, Bisevac M, et al. Effects of taurolidine and octreotide on port site and liver metastasis after laparoscopy in an animal model of pancreatic cancer. Clin Exp Metastasis, 2002, 19:169-173.
  • 5Schuller HM, Zhang L, Weddle DL, et al. The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK. J Cancer Res Clin Oncol, 2002, 128:525-532.
  • 6Guo YS, Townsend CM Jr. Role of gastrointestinal hormones in pancreatic cancer. J Hepatobiliary Pancreat Surg, 2000, 7:276-285.
  • 7Taylor PR, Dowling RH, Palmer TJ, et al. Induction of pancreatic tumours by longterm duodenogastric reflux. Gut, 1989 ,30:1596-1600.
  • 8Oettle H, Arnold D, Riess H. Adjuvant therapy of pancreatic carcinoma. Schweiz Rundsch Med Prax,2000,89:2017-2025.
  • 9Nanda GS, Sun FX, Hofmann GA, et al. Electroporation enhances therapeutic efficacy of anticancer drugs: treatment of human pancreatic tumor in animal model. Anticancer Res, 1998, 18:1361-1366.
  • 10Mohammad RM, Dugan MC, Mohamed AN, et al. Establishment of a human pancreatic tumor xenograft model: potential application for preclinical evaluation of novel therapeutic agents. Pancreas,1998, 16:19-25.

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