高原低氧性肺动脉高压的多普勒超声研究

A STUDY ON HIGH ALTITUDE HYPOXIC PULMONARY HYPERTENSION BY DOPPLER ECHOCARDIOGRAPHY

应用脉冲式或连续式多普勤超声技术，对１８例海拔３２００ｍ高原正常人及２５例高原性心脏病（ＨＡＨＤ）患者测定其肺动脉压。正常组及ＨＡＨＤ无瓣膜返流组１０例（４０％）应用Ｈａｈａｍ回归方程，ＰＡＭＰ分别为２．８４±０．４及３．７３±０．５７（ｌｋＰａ＝７．５ｍｍＨｇ）；ＨＡＨＤ有三尖瓣返流组８例（３２％）用ＴＲＰＧ法测得ＰＡＳＰ为６．１３±１．７３ｋＰａ；ＨＡＨＤ有肺动脉瓣返流组７例（２８％）用ＰＲＰＧ法测得ＰＡＤＰ为４．０±０．７３ｋＰａ。表明多普勒超声技术的不同方法可用于不同病理状态上高原低氧性肺动脉高压的测定，并揭示了出现瓣膜返流改变时高原低氧性肺动脉高压的程度。

he pulmonary artery pressure was evaluated by Doppler echocardiography in l8 healthy native su5jects at high altitude and 25 cases of high altitude heart disease(HAHD).Wifh Haham’s regressive formula,PAMP=(79-0.45×AT),PAMP was 2.84±0.lkPa in healthy subjectsand 3. 73±0.57in l0 cases of HAHD without valve reguritation(40%); PASP was 6.13±1.73kPa in 8 cases of HAHD with tricusPid regurgitation(32%)by TRPG method; PADP was 4.0±0.73kPa in 7 cases of HAHD with pulmonary regurgitation(28%)by PRPG method. The con-clusion was that the different methods of Doppler echocardiography can be used for cvaluating hy-poxic pulmonary hypertension at various pathologic stages,and the exrent of high altitudc hypoxicpulmonary hypertension which caused valve rcgurgitation was shown.