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基质金属蛋白酶组织抑制剂在心脏中的表达及意义 被引量：1

Expression and Function of Tissue Inhibitor of Matrix Metalloproteinases in Heart
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摘要 基质金属蛋白酶组织抑制剂在心血管疾病发生发展过程中的变化是近年来心血管领域研究的热点之一。现就基质金属蛋白酶抑制剂的分类和结构及在心肌重构、心力衰竭、心肌缺血再灌注损伤等的表达及作用作一综述。 The changes of tissue inhibitor of matrix metalloproteinases. （ TIMPs） during occurence and development of cardiovascular diseases is one of the hottest research points in cardiovascular field recently. The review summarized the style and structure of TIMPs and its expression and function in myocardial reconstruction and heart failure and myocardiac ischemia reperfusion injury.
作者 郑先杰 郭志坤
机构地区 新乡医学院心脏形态学教研室
出处 《心血管病学进展》 CAS 2005年第B08期109-111,共3页 Advances in Cardiovascular Diseases
关键词 基质金属蛋白酶组织抑制剂 心肌重构 心力衰竭 心肌缺血再灌注 Tissue inhibitor of matrix metalloproteinases Myocardial reconstruction Heart failure Myocardiac ischemia-reperfusion
分类号 R541 [医药卫生—心血管疾病]
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参考文献16

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  • 2Zhong ZD, Hammani K, Bae WS,et al. NF-Y and Spl cooperate for the transcriptional activation and cAMP response of human tissue inhibitor of metalloproteinase-2 [ J ]. J Biol Chem ,2000,275 ( 24 ) : 18602-18610.
  • 3Noji Y, Kajinami K, Kawashini MA, et al. Circulating matrix metalloproteinase and their inhibitors in premature coronary atheroselerosis [ J ]. Clin Chem Lab Med ,2001,39:380-384.
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引证文献1

心血管病学进展
2005年 第B08期

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