禽霍乱免疫母鸡血清抗体和蛋黄抗体消长规律及其相互关系的研究

STUDIES ON GBOWTH-DECLINE REGULARITY OF SERUM-AND YOLK-ANTIBODIES AND THEIR RELATIONSHIP IN IMMUNIZED LAYING HENS TO PASTEURELLA MULTOCIDA

通过对禽霍乱菌苗免疫产蛋母鸡的血清和蛋黄的抗体定时检测后发现，免疫母鸡的血清抗体和蛋黄抗体的升降趋势基本一致（ｒ＝０．９４），但后者较前者迟后３～６ｄ；血清抗体和蛋黄抗体的滴度分别在加强免疫后的１～３ｄ和３～６ｄ都有不同程度下降，加强免疫前的滴度越高，免疫后的滴度下降幅度越大；蛋黄抗体水平普遍比血清抗体水平低，两者间的差异极显著（Ｐ＜０．０１），这可能是与禽多杀性巴氏杆菌本身的主要抗原成分（ＴＩ抗原）在鸡体内主要产金ＩｇＭ有关。

Through determining the serum-and yolk-antibody titers in immunized laying hensto Pasteurella mullocida regularly,it was found that the growth-decline trend of theyolk antibodies was similar to that of the serum antibodies(r=0.94),but the growthand decline of the yolk antibody titer delayed 3-6 days as compared with that of theserum antibody titer.Tlie serum-and yolk-antibody levels might have some decline afterbooster immunizations 1-3 and 3-6 days respectively,and the higher level of antibodybefore booster immunization.the lower decline extent of the antibodv level after thebooster immunization in above time.The yolk antibody titers were generally lower thanthat of serum antibody titers(P<0.01),which seeln to be in connection with the anti-gen construction of Pasteurella multocida(mainly TI antigen)and mainly producingIgM in the immunized laying hens.