孕妇人群HBV流行状况分析

Analysis of HBV Epidemic Status among Pregnant Women

目的分析合肥地区孕妇人群中HBV的流行状况.方法在产前常规检查中,采用酶联免疫吸附试验检测孕妇HBV标志物.应用Epi Info 6.04建立数据库,SPSS软件进行分析.结果2002～2004年共检测3 415例孕妇,HBsAg携带率3.34%(114/3 415),城镇孕妇HBsAg携带率(2.91%)显著低于农村孕妇(5.62%)(P＜0.01);不同年龄组孕妇HBsAg携带率的差异无显著性(P＞0.05).结论合肥地区孕妇HBsAg携带率较低,对孕妇进行HBV筛查有利于预防HBV母婴传播的发生.

Objective To explore epidemic status of hepatitis B virus （HBV） among pregnant women in Hefei city. Methods Serological HBV markers were tested by ELISA among pregnant women under routine examination before delivery. EPI software package was used to set up database and the data was analyzed by SPSS. Results Total of 3 415 pregnant women were tested in Hefei city from 2002 to 2004,and HBsAg carrying rate was 3. 34%. Significant difference was found between pregnant women in the city （2.91%） and those in countryside（5.62 %）（P〈0.01）. HBsAg carrying rate among pregnant women was not correlated with the age（P〉0. 05）. Conclusion HBsAg carrying rate is low among pregnant women in Hefei. The rate of HBsAg among pregnant women in the city is significantly lower than that in countryside. HBV screening among pregnant women shoud be carried out to prevent HBV transmission.