肝硬化门脉高压性胃病与幽门螺杆菌感染及NO水平的关系

Investigation of the relationship between portal hypertensivegastropathy(PHG)and infection of helicobacter pylori(HP)or nitric oxide level

目的探讨门脉高压性胃病(PHG)与幽门螺杆菌(HP)感染或血清NO浓度之间的关系。方法PHG患者60例,通过内镜检查诊断,胃黏膜活检(每例4块)用改良Giemsa染色法检测HP。NO测定采用硝酸还原酶法。结果PHG患者的HP阳性率为68.3%(41/60),PHG组与对照组胃液或血清NO水平比较,差异有显著性(P<0.05);HP阴性与阳性组PHG胃液或血清NO水平之间比较,差异有非常显著性(P<0.01)。结论PHG患者的胃黏膜病变与HP感染有密切关系。

Objective To study the relationship between portal hypertensivegastropathy（PHG） and infection of helicobacter pylori（HP） or NO. Methods PHG patients（n=60） were investigated by endoscopy and 4 mucosal biopsy samples from each patient were studied by reformed Giemsa stain method. Results The total positive rate of HP infection in PHG patients were 68.3%（41/60 eases）. In PHG with peptic ulcer it was 53. 7%（22/41 cases）,and in simple PHG without peptic ulcer it was 46.3% （19/41 eases）. Conclusion There is a close relation between gastric mucosal lesions of PHG and infection of HP.