肾衰丸中大黄素的含量测定

Determination of emodin in Shenshuai pills by RP-HPLC

目的:控制肾衰丸的质量,以保证用药安全有效。方法:用高效液相色谱法对大黄素进行含量测定。结果:大黄素加样回收率为98.86%,RSD为1.73%(n=5),3批样品中大黄素的含量分别为0.412,0.407,0.396mg/粒。结论:本方法简便,快速,结果可靠,可作为肾衰丸的质量控制手段。

OBJECTIVE To control the quality standard and guarantee the effective and safe use of Shenshuai pills. METHODS Emodin of Shenshuai pills was determined by HPLC. RESULTS Average recovery was 98.86% with RSD of 1.73%. The contents of Shenshuai pills in three batches were 0. 412, 0. 407, 0. 396 mg/pill respectively. CONCLUSION The method is simple, reliable and can be used for controlling the quality of Shenshuai pills.