摘要
①目的探讨急性脑梗死病人血清瘦素、白细胞介素6水平的变化。②方法60例脑梗死病人,入院后第2天抽取空腹静脉血,用ELISA法检测血清瘦素及白细胞介素6水平,同时检测21例健康成人血清作为对照。③结果脑梗死组瘦素及白细胞介素6水平显著高于对照组(t′=6.67,t=4.65,P<0.01)。④结论急性脑梗死存在高瘦素血症和瘦素抵抗,瘦素水平增高是急性脑梗死的危险标志。白细胞介素6参与了急性脑梗死的发生发展。
Objective To study the changes of interleukin-6 （IL-6） and leptin in patients with acute cerebral infarction. Methods Blood samples from 60 patients with cerebral infarction and 21 controls were collected. The levels of leptin and IL-6 were detected by radioimmunoassay. Results Serum leptin and IL-6 levels in the patients were higher than those in normal controls （t′=6.67,t=4. 65,P〈0.01）. Conclusion There is hyperleptinemia and leptin resistance in acute cerebral infarction. High serum leptin is a risk sign of acute infarction. IL-6 is involved in the occurrence and development of the disease.
出处
《齐鲁医学杂志》
2005年第6期483-484,共2页
Medical Journal of Qilu
关键词
瘦素
白细胞介素6
脑梗死
leptin
interleukin-6
cerebral infarction
