适应性压力通气治疗新生儿呼吸衰竭

Adaptive Pressure Ventilation Treatment in Neonatal Respiratory Failure

目的:观察应用适应性压力通气(APV)治疗新生儿呼吸衰竭的效果。方法:比较15例APV与17例CMV模式治疗的新生儿呼吸衰竭患者需要机械通气支持的平均时间、第一次血气恢复至正常范围时平均的机械通气各参数及并发症的差异。结果:APV模式治疗组第一次血气恢复正常时平均PIP及MAP较CMV治疗组降低,差异有显著性;PEEP、RR、FiO2及需要机械通气的平均时间两组差异无显著性。结论:APV模式可安全应用于新生儿及早产儿呼吸衰竭的治疗,能降低PIP及MAP,有利于减少肺气压伤的发生。

Objective：To investigate the effect of APV treatment in neonatal respiratory failure. Method： Comparing the duration of ventilation,parameters of ventilation at the first point of normal blood gas analysis obtained and complications between 15 cases of neonates with respiratory failure treated by APV and 17 cases treated by CMV. Results： The mean of PIP and MAP at which the first blood gas analysis recovering to normal of APV group were significantly lower than that of the CMV group. There were no significant differences of PEEP,RR,FiO2 and the duration of ventilation between two groups. Conclusion： The APV can decrease PIP and MAP needed by which barotraumas of lung are reduced. The APV is a safety ventilation mode in the treatment of respiratory failure of neonate and premature newborn.