用COLOC谱研究线型二氢吡喃香豆素Pd—C—I酰基连接位置

STUDY OF ATTACHED POSITION OF ACYL GROUP OF LINEAR DIHYDROPYRANOCOUMARINS Pd-C-I BY COLOC

用ＣＯＬＯＣ技术并结合１Ｈ－１ＨＣＯＳＹ谱对线型二氢吡喃香豆素类化合物Ｐｄ—Ｃ—Ｉ的化学结构进行了深入研究．证实该类化合物酰基连接位置可用ＣＯＬＯＣ谱确定．这对这类化合物的结构研究和构效关系的探讨均有重要意义，另外利用２ＤＮＭＲ修正了文献中对Ｐｄ—Ｃ—Ｉ部分碳氢信号归属的错误．

The chemical structure of linear dihydropyranocoumarins Pd C I was studied in detail by COLOC spectrum as well as 1H 1H COSY spectrum.It was observed that the attached position of acyl group of Pd C I can be determined by correlated cross peaks in COLOC spectrum.The result shows the significance on structural studies and discussion of structure activities relationship of linear dihydropyranocoumarins.The mistakes in the literatures about the assignments of some signals of carbons and protons were also revised.