摘要
以水杨酸为模型药物,分别对巴马小香猪皮肤与人的皮肤进行Franz扩散池的药物渗透实验.结果表明,巴马小香猪皮肤和人的皮肤的药物渗透性极为相似,证明了巴马小香猪是较理想的透皮吸收研究的实验动物模型.
In this study, using Franz diffusion cells, we copare transdermal permeation of salicylie acid in human with Bama minipig. It was found that the permeation in Bama minipig is very similar with human. The results indicated that Bama minipig is bery good as animal model in transderaml permeantional research.
关键词
巴马小香猪
皮肤
水杨酸
透皮吸收
Bama minipig
skin
salicylie acid
transdermal permeation
