健康成年人左心室形态和功能的磁共振成像研究

MRI to evaluate modality and function of normal left ventricular in adult

目的:探讨磁共振成像测量左心室形态及功能的方法和准确性。方法:应用磁共振成像仪对40例健康成年人进行图像扫描及后处理分析,分别用短轴位、长轴位、四腔心位测量左心室室壁和室间隔的厚度、心腔大小,屏气电影法测量计算左心室容积和功能。结果:左心室室壁和室间隔的厚度、心腔大小的测量值、舒张末期容积、收缩末期容积及心肌重量男性均大于女性,差异有显著性意义(P<0.05);但左心室短径的收缩末期径线男女无显著性差异(P>0.05);左心室心肌重量与身高的比值、射血分数与年龄无关;经身高的调整,各测量值仍是男性大于女性(P<0.02);经体表面积的调整,心室容积(包括舒张末期和收缩末期)、心肌重量的测量值男性大于女性(P<0.05),女性左心室心腔大小与体表面积的比值增加,而且舒张末期横径与体表面积的比值女性大于男性(P<0.05)。结论:左心室的室壁厚度、心腔的大小、心室的功能,均与性别、个体大小有关,磁共振成像能准确测量左心室的室壁厚度、心腔的大小,且能计算心室功能,是一种临床实用价值很高的技术。

Objective：To evaluate the ways and veracity of MRI in measuring adult of normal left ventricular. Methods： Forty cases of clinically overt cardiovascular disease underwent respectively cardiac MR imaging examination to determine LV wall thickness, cavity length, LV function. Results： Unidimensional measures of LV wall thickness, cavity length, EDV, EDS, mass were significantly greater （ P 〈0.05） in men than in women and remained greater （ P 〈0.02） after adjustment for subject height. Volumetric measure were greater （ P 〈0.05） in men than in women after adjustment for body surface area（BSA）, but there were increased linear dimensions in women after adjustment for BSA, end-diastolic short dimension was no difference as in women （ P 〉0.05）. There were no age differences in mass adjustment for height and LVEF. Conclusion：MRI measure of LV wall thickness,cavity length, LV function differ significantly according to gender and body size. MR imaging was a useful method for evaluating the left ventricular function because of non-ghosting artifacts and short imaging time.