经皮穿脾选择性门静脉栓塞术在中晚期肝癌综合治疗中的应用

Percutaneous transsplenic selective portal vein chemoembolization in comprehensive treatment of advanced liver cancer

目的探讨经皮穿脾选择性门静脉栓塞术(PTSPVCE)在中晚期肝癌综合治疗中的应用价值。方法在TACE术后,对8例有门静脉供血的肝癌患者,在X线引导下采用经皮穿脾方法行选择性门静脉化疗栓塞。与单纯TACE组比较疗效和并发症。结果实验组术后肿块缩小率明显优于对照组(P<0.05)。无严重并发症。结论PTSPVCE术是一种安全、可靠的疗法,为肝癌的综合治疗提供了更多的选择。

Objective To evaluate the value of percutaneous transsplenic selective protal vein chemoembolization （PTSPVCE） in the comprehensive treament of advanced liver cancer. Methods Twenty-one patients with advanced liver cancer underwent transcatheter arterial chemoembolization （TACE）. After TACE, eight of them were treated with PTSPVCE. The volume of tumor, changes of hepatic function and complication were compared betweem two groups. Resuits There was significant difference between study group and control group. The tumor shrinkage was observed in study group with no recurrence of serious complications. Conclusion PTSPVCE is safe, reliable and efficient for the treament of advanced liver cancer.