立体定向放射外科治疗小儿脑动静脉畸形100例报告

Stereotactic radiosurgery in the treatment of arterionvenous malformation in children: report of 100 cases

目的探讨应用γ-刀治疗小儿脑动静脉畸形(AVM)合理有效的治疗方案及其并发症的预防。方法选择100例经手术/DSA/MRA证实的1至14岁脑AVM患儿,应用γ-刀治疗并总结效果。结果随访平均18个月,根据临床表现及影像学复查结果判断预后,总有效率为93.7%。结论γ-刀治疗小儿脑AVM是一种安全、有效、创伤小、痛苦少的方法,但要严格掌握适应证,严谨治疗方法,尽可能避免并发症的发生。

Objective To find out the reasonable therapy of intracranial arterionvenous malformation （AVM） and of its complications in children treated with gamma knife. Methods 100 patients aged 1-14 years confirmed AVM by surgical, DSA or MRA were treated with gamma knife and followed up for an average period of 18 months. The clinical manifestations and the re-examined images were taken into the evaluation of the reasonability and effectiveness of the treatment and prevention of the complications. Results The total effective rate was 93.7% in the children patients with AVM. Conclusion As an approach to treating the intracranial AVM in children, gamma knife is safe, effective, less traumatic and less painful on conditions of avoidance of its possible complications by way of rigorous performance of therapy.