摘要
心力衰竭是心脏疾病的终末阶段,其特征是心脏收缩舒张功能紊乱,心脏排血量不足,并且伴随着一系列的并发症状。近年来,国内外深入地研究了引起犬发生心力衰竭的各种病理机制。这些机制主要包括内皮素系统、一氧化氮、Ca2+、肾上腺及其受体和肾素-血管紧张素系统的病理生理作用,以及在发生心力衰竭时的心肌细胞及细胞外基质的病理变化。详细地了解这些发病机制,可为临床上更好的治疗心力衰竭以及选择合适的治疗药物提供理论依据。
Heart failure is the final period of heart diseases, which is characterized by function disorder of heart contract-stretch, deficiency of blood ejection, and with a series of symdromes. The pathologic mechanisms had been studied deeply these years. This article referred to literatures of home and abroad, summarized the pathologic mechanism of heart failure in detail. This mechanism involved pathologic and physiologic effect of Endothelin system,NO. Ca^2＋ . adrenalin and hypertension.the pathologic changes of cardiac muscle cell with heart failure happening. Studying the mechanism intensively is to treat heart failure effectively and select suitable drugs.
出处
《动物医学进展》
CSCD
2005年第9期17-21,共5页
Progress In Veterinary Medicine
关键词
心力衰竭
病理机制
heart failure
pathologic mechanism
