摘要
本研究首先采用非线性骨再造速率方程和有限元方法相结合,引入拓扑优化思想,从不确定外形出发,模拟了正常力学环境下的胫骨上端外部形状和内部结构。然后以得到的正常力学环境下的胫骨上端外部形状和内部结构为初始模型,根据骨质增生形成的过程,提出膝内翻时胫骨平台上所受压力的分布随内翻角度的变化以及骨质增生过程中平台上受力分布和骨刺上压力分布改变的假设。模拟了膝内翻引起胫骨平台内侧的骨质增生。在模拟的过程中,总结出了一种符合骨质增生生理过程的模拟方法。
In this paper a nonlinear equation of bone-remodeling combining with FEM was proposed by introducing topology optimization in engineering. The interior structure and the exterior shape of the upper tibiae under normal load situation were simulated from unfixed configurations. Based on the simulative structure model and formation process of osseous hyperplasia, a hypothesis was forwarded, that is: under the varus situation, the load distribution on the edge of the flat roof of the tibia varied with the variation of the varus angle; During the process of osseous hyperplasia, the load distribution on the roof of the tibia and the pressure distribution on the spur changed. The osseous hyperplasia of inboard flat roof of the tibia caused by varus was simulated, during the process of simulating, a new simulating method matching the physiological forming process of the osseous hyperplasia was established.
出处
《中国生物医学工程学报》
EI
CAS
CSCD
北大核心
2005年第4期391-396,共6页
Chinese Journal of Biomedical Engineering
基金
吉林省科委发展计划项目(20010527)
博士点基金资助项目(20020183025)
国家自然科学基金资助项目(10372034)
关键词
骨再造非线性方程
拓扑优化
有限元方法
骨质增生
膝内翻
nonlinear equation of bone-remodeling
topology optimization
FEM
osseous hyperplasia
varus