2Pizzuti A,Frittitta L,Argiolas A,et al.A polymorphism(K121Q)of the human glycoprotein PC-1 gene coding region is strongly associanted with insulin resistance[J].Diabetes,1999,48(9):1 881～1 884.
3Frittitta L,Baratta R,Spampinato D,et al.The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance[J].Clin Endocrinol Metab,2001,86(12):5 888～5 891.
5Frittitta L,Spampinato D,solini A,et al.Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects[J].Diabetes,1998,47(7):1 095～1 110.
6Maddux BA,Goldfine ID.Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor ɑ-subunit[J].Diabetes,2000,49(1):13～19.
7Shulman Gl.Cellular mechanism of insulin resistance[J].Clin Invest,2000,106(2):171～176.
8Pessin JE,Saltiel AR.Singaling pathways in insulin action:molecular targets of insulin resistance[J]. Clin Invest,2000,106(2):165～169.
9Whitehead JP,Humphreys PJ,Dib K,et al.Expression of the putative inhibition of the insulin receptor tyrosine kinase PC-1 in dermal fibroblasts from patients with syndromes of severe insulin resistence[J].Clin Endocrinol(Oxf),1997,47(1):65～70.
10Kumakura S,Maddux BA,Sung CK.Overexpression of membrane glycopprotein PC-1 can influence insulin action at a post-receptor site[J].J Cell Biochem,1998,68(3):366～377.
二级参考文献15
1Stefanovic V,Antic S,Mitic-Zlatkovic M,et al.Reversal of increased lymphocyte PC-1 activity in patients with type 2 diabetes treated with metformin[J].Diabetes Metab Res Rev,1999,15:400-404.
2Ozel B,Youngren J F,Kim J K,et al.The development of insulin resistence with high fat feeding in rats dose not involve either decreased insulin receptor tyrosine kinase activity or membrane glycoprotein PC-1 [J].Biochem Mol Med,1996,59:174-181.
3Sakoda H,Ogihara T,Anai M,et al.No correlation of plasma cell 1 overexpression with insulin resistance in diabetic rats and 3T3-L1 adipocytes [J].Diabetes,1999,48:1365-1371.
4Stefan C,Wera S,Stalmans W,et al.The inhibition of the insulin receptor by the membrane protein PC-1 is not specific and results from hydrolysis of ATP [J].Diabetes,1996,45:980-983.
5Youngren J F,Maddux B A,Sasson S,et al.Skeletal muscle content of membrane glycoprotein PC-1 in obesity [J].Diabetes,1996,45:1324-1328.
6Frittitta L,Camastra S,Baratta R,et al.A soluble PC-1 circulates in human plasma:relationship with insulin resistance and associated abnormalities [J].J Clin Endocrinol Metab,1999,84:3620-3625.
7Maddux B A,Goldfine I D.Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor α-subunit [J].Diabetes,2000,49:13-19.
8Frittitta L,Youngren J,Vigneri R,et al.PC-1 content in skeletal muscle of non-obese,non-diabetic subjects:relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity [J].Diabetologia,1996,39:1190-1195.
9Frittitta L,Spampinato D,Solini A,et al.Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects [J].Diabetes,1998,47:1095-1110.
10Belfiore A,Costantino A,Frasca F,et al.Overexpression of membrane glycoprotein PC-1 in MDA-MB231 breast cancer cells is associated with inhibition of insulin receptor tyrosine kinase activity [J].Mol Endocrinol,1996,10:1318-1326.
